Insect growth regulators are generally harmless to humans and other vertebrates. Is this statement true or false?

The statement is true because insect growth regulators (IGRs) are designed to disrupt the development process of insects, specifically targeting their hormonal systems. They interfere with processes such as growth, molting, and reproduction in pests, but they have a different mode of action compared to traditional insecticides.

IGRs typically target specific receptors found in insects and are not present in humans or other vertebrates, which is why they are considered to be generally harmless to these organisms. This selective action minimizes their toxicity and potential side effects in non-target species, making them a safer option for controlling pest populations.

While some precautions are always advisable when handling any chemical, the design and mechanism of IGRs contribute significantly to their safety profile for humans and other mammals.